Huge Fantasy Baseball Trade! Should I do it?

Absolutely. Now that Ryan Ludwick is back in the lineup, Pujols is now getting more pitches to hit. In fact, he had more home runs this weekend then when Ludwick was gone (2 to 1)! Also, Ramirez is starting to hit. Besides, Sizemore just went on the DL, so he'll be gone for a while. So if you have a good back-up 3B or good ones available on FA, I strongly recommend going after it.